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Human evolution – plagues, pathogens and selection









Kavli Royal Society Centre, Chicheley Hall, Newport Pagnell, Buckinghamshire, MK16 9JJ



Organised by Professor Danny Altmann, Dr Francois Balloux and Dr Rosemary Boyton

In this Satellite meeting we aim to bring together an international cohort of academics from highly diverse backgrounds so that anthropologists, historians, geneticists, immunologists, molecular microbiologists and experts on the evolution of language can together bring their knowledge to bear on plotting the timeline of human history and the forces that have shaped it. We will consider the co-evolution of man, our immune system and our major pathogens, taking into account recent evidence from DNA sequencing initiatives alongside the evidence from historical artifacts.

Programme available to download here.

Event organisers

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Schedule of talks

Session 1

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Death comes to town: disease resistance, urbanisation and recent selection in human populations

Dr Ian Barnes, Royal Holloway, University of London, UK

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Hunting the molecular past

Professor Eske Willerslev, University of Copenhagen, Denmark

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African population history inferred from genomic data

Dr Brenna Henn, Stanford University, USA

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Archaeogenetics and the settlement of the Remote Pacific

Professor Martin Richards, University of Leeds, UK

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Session 2

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Insights into human genome variation from the 1000 Genomes Project

Dr Chris Tyler-Smith, Wellcome Trust Sanger Institute, UK

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Language evolution in time and space

Dr Quentin Atkinson, The University of Auckland, New Zealand

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Reconstruction of ancient migrations using multiple lines of evidence

Dr Stephen Oppenheimer, Institute of Cognitive and Evolutionary Anthropology, School of Anthropology and Museum Enthnography, University of Oxford, UK

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Reconstructing the mode and tempo of the out-of-Africa migration of anatomically modern humans

Dr Andrea Manica, University of Cambridge, UK

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Session 3

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Evolution of the HLA-C 3’UTR and its effect on HIV control

Dr Mary Carrington, National Cancer Institute, USA

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Population-specific evolution of Natural Killer cell diversity

Dr Paul Norman, Stanford University, USA

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Origin of Amerindians and their genetic relatedness with Asian and Pacific islanders

Dr Antonio Arnaiz-Villena, Universidad Complutense, Spain

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Recognition of the Mtb-infected Cell: a fine line between innate and adaptive immunity

Professor David Lewinsohn, Oregon Health & Science University, USA

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Session 4

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Are occasional human pathogens useful to their host?

Professor Robin Weiss FRS, University College London, UK

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Should we blame agriculture on all our ills

Dr Francois Balloux, Imperial College London, UK and Switzerland

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The role of epistatic interactions between genetic disorders of haemoglobin in determining their global distribution

Professor Sunetra Gupta, University of Oxford, UK

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Human evolution – plagues, pathogens and selection Kavli Royal Society Centre, Chicheley Hall Newport Pagnell Buckinghamshire MK16 9JJ