Sir Alec Jeffreys CH FMedSci FRS
Alec Jeffreys is a now-retired geneticist who was one of the first to discover inherited variation in human DNA. He developed the milestone techniques of genetic fingerprinting and profiling, using variations in the genetic code to uniquely identify people. These are now widely used in forensic science and paternity testing, and have directly affected the lives of over 50,000,000 people worldwide.
Alec went on to investigate how variation in DNA comes about when DNA is transmitted from parent to child. He developed new methods to characterise rare new mutations in DNA as well as places in chromosomes where DNA is reshuffled by recombination. He identified recombination hotspots where most reshuffling occurs and carried out pioneering work to understand how these hotspots work.
Alec was knighted in 1994 for services to science and technology.
Interest and expertise
- Organismal biology, evolution and ecology
DNA, forensics, Germline mutation, Homologous recombination, Illegitimate recombination, Human genetics, Human genomics