Allan Bradley is a geneticist who has made fundamental contributions to our understanding of embryonic stem (ES) cells and DNA manipulation. Allan’s experiments have opened up a new line of research for biologists based on techniques for modifying endogenous genes in mice.
He was first to demonstrate that following injection into pre-implantation blastocysts, ES cells can be transmitted through the sperm and eggs of the resulting mice. Allan later reported that such techniques could be used to generate mice containing specific gene mutations — work that contributed to the 2007 Nobel Prize in Physiology or Medicine.
From 2000–2010, Allan served as Director of the Wellcome Trust Sanger Institute in Cambridge. During this time, he established a new direction for the institute and initiated the largest gene knockout project ever attempted on ES cells. In 1994, he received the DeBakey Award of Baylor College of Medicine for his work on chromosome engineering in ES cells.
Director of Studies, Cambridge Institute for Therapeutic Immunology and Infectious Disease, University of Cambridge
Interest and expertise
Microbiology, immunology and developmental biology
Genetics (excluding population genetics), Developmental biology