Bryan Charleston is the Director of the Pirbright Institute since 2015, with responsibility for the diagnosis and control of exotic viral diseases of livestock in the UK and worldwide, for example foot-and-mouth disease and African swine fever.
A major programme of work initiated by Bryan has demonstrated for the first time the epidemiological significance of African buffalo persistently infected with foot-and-mouth disease virus, to maintain the virus in wild populations and transmit to farmed animals.
Bryan has led a team to design novel virus-like-particle vaccines for foot-and-mouth disease. These new vaccines can be produced in low biosecurity facilities and are thermostabilised by structural modifications, to help address the global under supply of vaccine. Bryan's work has also made significant contributions to the development of many novel vaccines for livestock and zoonotic diseases.
Bryan's commitment to the development of vaccines to control major livestock and zoonotic diseases in low- and middle-income countries, has driven the establishment of a Centre for Veterinary Vaccine Innovation and Manufacturing at Pirbright.
Director and CEO, The Pirbright Institute
Interest and expertise
Microbiology, immunology and developmental biology
General microbiology (incl bacteriology and virology)