Professor Alan Robert Lehmann FRS
Chairman, Genome Damage and Stability Centre and Professor of Molecular Genetics, School of Life Sciences, University of Sussex.
Alan R. Lehmann is distinguished for his use of molecular biology, genetics and cell biology to understand the mechanisms of DNA repair and to elucidate defects in these processes in several human genetic disorders. His most significant contribution has been the insights he has provided into the way in which cells are able to replicate damaged DNA. He showed that xeroderma pigmentosum variant patients were defective in this ability, he characterised numerous aspects of this process and showed how a specialised DNA polymerase is employed to replace the replicative polymerase blocked at DNA damage. Lehmann's work has provided deep insights into the relationship between DNA repair and cancer.