Dr Steven J. Gamblin FRS
Director of Research, MRC National Institute for Medical Research
Steven Gamblin's research has provided critical insights into the fundamental mechanisms underlying cellular signalling and disease processes. The crystallographic studies on the influenza haemaglutinin (HA) from the 1918 strain explain the basis of the viruses' specificity and the contribution of HA to the devastating mortality of this pandemic virus. Research on SET proteins, and the pRb tumour suppressor have offered powerful insights into how eukarotic cells regulate transcription while that on small GTPases and 14-3-3 has shown how these key signalling pathways function. His authority in research rests on his ability to identify questions that really matter and answer them.