Professor Shankar Balasubramanian FMedSci FRS
Herchel Smith Professor of Medicinal Chemistry, Department of Chemistry, University of Cambridge and Senior Group Leader, Cancer Research UK, Cambridge Research Institute
Shankar Balasubramanian is an internationally recognised leader in the field of nucleic acids who is distinguished for pioneering contributions to chemistry and its application to the biological and medical sciences. He is a principal inventor of the leading next generation sequencing methodology, Solexa sequencing, that has made routine, accurate, low-cost sequencing of human genomes a reality and has revolutionised biology. He has made seminal contributions to the identification, elucidation and manipulation of non-coding genetic elements, particularly four-stranded structures called G-quadruplexes. His work on the intervention of nucleic acid function using small molecules has revealed a number of molecular mechanisms that can be exploited, e.g. to modulate the biology of cancer.