Research Fellows Directory
Miss Honglei Liu
University of St Andrews
Cyclic compounds are widely presented in natural products and synthetic pharmaceuticals. Annulation reaction is a powerful tool for synthesis of cycles from starting materials under mild condition. My research interest is focused on the development of new annulation reactions. Through using zwitterion as reactive intermediate, I studied metal-catalyzed cycloaddition reactions of reactive dipolar species with stable 1,3-dipoles and Lewis base-catalyzed cycloaddition reactions of reactive dipolar species with stable 1,3-dipoles. In addition, with the use of chiral organocatalyst or metal catalyst, asymmetric cycloaddition reactions have been explored to efficiently synthetize cyclic compounds containing multi chiral centers with good enantioselectivity and diastereoselectivity.
Interests and expertise (Subject groups)