Scheme: University Research Fellowship
Organisation: University of Durham
Dates: Oct 2014-Sep 2017
Summary: Our primary research interest is the synthesis of biologically interesting molecules which encompasses the design, development and integration of new processing techniques for their preparation and solving of challenges associated with the syntheses of new pharmaceutical and agrochemical compounds. In our work we utilise the latest synthesis tools and enabling technologies such as microwave reactors, solid-supported reagents and scavengers, enzymes, membrane reactors and flow chemistry platforms to facilitate the bond making sequence and expedite the purification procedure. A central aspect of our investigations is our pioneering work on flow chemical synthesis and microreactor technology as a means of improving the speed, efficiency, and safety of various chemical transformations. As a part of these studies we are attempting to devise new chemical reactions that are not inherently feasible or would be problematic under standard laboratory conditions. It is our further challenge to enhance the automation associated with these reactor devices to impart a certain level of intelligence to their function so that repetitive wasteful actions currently performed by chemists can be delegated to a machine; for example, reagent screening or reaction optimisation. We use technology as a tool to enhance our synthetic capabilities expanding access to new chemical entities.
Dates: Oct 2009-Sep 2014