Professor Jeremy Sanders CBE FRS
Jeremy Sanders developed innovative applications of NMR spectroscopy in organic and biological chemistry, and is known for his biomimetic porphyrin systems and his theory of pi–pi interactions. His early explorations of lanthanide shift reagents and NOE difference spectroscopy enhanced the power of NMR to solve organic chemical structure and conformation.
His most notable contribution to biological chemistry through NMR was to resolve many of the long-standing paradoxes between the known in situ enzymology and the apparently contradictory physical chemistry of isolated polyhydroxybutyrate storage granules in bacteria.
Since the 1990s, he has developed the concept of dynamic combinatorial chemistry as a new approach to the discovery of new structures that are capable of binding and catalysis. Using reversible reactions to connect a variety of building blocks, it is possible to use templates to amplify successful receptors. It is also possible to use self-templating, for example through donor–acceptor and hydrophobic effects in water, to generate otherwise inaccessible catenanes and molecular knots in water.
Pro-Vice-Chancellor, University of Cambridge
Professor of Chemistry, Department of Chemistry, University of Cambridge
Interests and expertise
For his pioneering contributions to several fields, most recently to the field of dynamic combinatorial chemistry at the forefront of supramolecular chemistry.