Research Fellows Directory
Professor Lucy Walker
University College London
My research is focused on understanding how immune responses are initiated and regulated and how defects in these processes can cause autoimmune diseases. My group has a particular interest in type 1 diabetes which is known to be triggered by aberrant T-cell responses against the insulin-producing cells in the pancreas. The incidence of type 1 diabetes is rising fast and the UK now has the 5th highest diagnosis rate in the world. The reasons for this increase are unclear but the cost to society, both in terms of quality of life and the economic burden on the NHS, is significant.
Our goal is to characterize the particular T cells responsible for causing autoimmune diabetes and to define the molecular switches that control them. This information will allow the development of more refined medicines to treat, and maybe even prevent, this condition.