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Fellows Directory

Malcolm Brown

Professor Malcolm Brown FRS

Fellow


Elected: 2004

Biography

Malcolm Brown is a neuroscientist best known for his studies into the neural bases of learning and memory. Malcolm studies the responses of cells (neurons) in the brain whilst memory tasks are being performed. His aim is to expand understanding of memory mechanisms by establishing exactly which changes in the brain are crucial to memory. His work has enhanced our understanding of conditions that affect memory, such as Alzheimer’s disease.

Malcolm’s highly revealing experiments have expanded our knowledge of the neural bases of memory. In particular, by recording the activity of single neurons in animals performing recognition memory tasks, he found that the perirhinal cortex of the brain is essential for long-term recognition memory. This important work overturned previous theories concerning mechanisms of memory.

He is currently Emeritus Professor of Anatomy and Cognitive Neuroscience at the University of Bristol, and has been a key contributor to the Centre for Synaptic Plasticity — a joint venture between the university and the Medical Research Council. Malcolm has published over 100 papers in his field.

Interests and expertise

Subject groups

Keywords

Behavioral neuroscience, Hippocampus, Learning and memory, neuronal responses, perirhinal cortex, Synaptic plasticity