Matthew Rosseinsky has made influential discoveries in the field of materials chemistry, particularly in the synthetic chemistry of solid state electronic materials and novel microporous structures, which have applications ranging from catalysis to superconductivity. He works on the development of new methods of identifying functional materials, emphasising the integration of experiment with computational methods.

He has published 390 papers, including 14 and 8 in the multidisciplinary journals Nature and Science, respectively. In 2009, Matthew received the inaugural De Gennes Prize from the Royal Society of Chemistry (RSC) — a lifetime achievement award in materials chemistry that is open internationally and is one of the RSC’s three premier awards. He was awarded the Hughes Medal of the Royal Society in 2011, and its Davy Medal in 2017. He is currently a Royal Society Research Professor (since 2013). In 2017, he was Muetterties Lecturer at the University of California, Berkeley and the Lee Memorial Lecturer at the University of Chicago.