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Research Fellows Directory

SOHAM MITRA

Dr SOHAM MITRA

Research Fellow

Organisation

University of Edinburgh

Research summary

In developing cortex, new neuronal cells generate from its precursor cell types- radial glial cells/neural progenitor cells. After differentiation and proliferation of the neural progenitor cells, those newborn neuronal cells migrate to its proper position. Now the questions remain elusive that which factors determine when these neuroprogenitor cells will start to differentiate to neurons, when and where to migrate? Certain transcription factors control certain protein syntheses that promote neuronal birth determination and newborn neuronal target specific migration. Pax6 is a important transcription factor, control all the functions by changing several gene expression profiles that results in quantitative and qualitative increase of such kind of proteins that controls neuronal fate determination, neurogenesis and neuronal migration. Therefore the present study has been initiated with the aims to explore the impact of transcription factor Pax6 on gene expression during corticogenesis

Interests and expertise (Subject groups)

Grants awarded

Unraveling the impact of transcription factor Pax6 on gene expression during corticogenesis

Scheme: Newton International Fellowships

Dates: Jun 2016 - Jun 2018

Value: £99,000

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