Sir Stanley Peart FMedSci FRS
Stanley Peart is a doctor and clinical researcher who was first to demonstrate the release of noradrenaline after the stimulation of sympathetic nerves. However, Stanley’s main research interest lay in renal medicine and in particular, a hormone system that regulates blood pressure and water called the renin–angiotensin system.
He was the first to purify the peptide hormone angiotensin and determine its structure. He later isolated the enzyme renin — which catalyses the production of angiotensin — and carried out important work to investigate the control of its release in the body. Stanley is also acknowledged as being the driving force behind the development of the renal transplant programme at St Mary’s Hospital in Paddington, London.
Stanley was Chair of the Medical Research Society for more than a decade and later a member of the Medical Research Council. Stanley was also a trustee of the Wellcome Trust, where he headed their first clinical panel. He was knighted in 1985.
For his contribution to the foundations of understanding of the renin angiotensin system in particular through his seminal work on the isolation and determination of the structure of angiotensin, purification of renin, and subsequent studies on the control of renin release.