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Readers, writers and erasers

Scientific meeting

Location

Kavli Royal Society Centre, Chicheley Hall, Newport Pagnell, Buckinghamshire, MK16 9JJ

Overview

Satellite meeting organised by Professor A Ganesan, Professor Marianne Rots, Dr Paola Arimondo and Dr Akane Kawamura.

Nucleosome

Epigenetics refers to the control mechanisms that determine which genes are turned on or off in eukaryotic organisms. Epigenetics is fundamental to normal development and an organism’s response to the environment while its dysregulation is linked to disease conditions. This interdisciplinary meeting will bring together chemists and biologists that are internationally leading in cutting edge areas of epigenetics.

The schedule of talks and speaker biographies are available below. Speaker abstracts will be available closer to the meeting date. Recorded audio of the presentations will be available on this page after the meeting has taken place.

Call for abstracts - deadline Wednesday 5 April

There is the opportunity to give a short presentation at this meeting. If you would like to apply to give a short presentation, please submit your proposed title, abstract (not more than 200 words and in the third person), name of the proposed presenter and institution to the Scientific Programmes team no later than Wednesday 5 April. Please include 'Short presentation abstract submission' in the email subject line. Please note places are limited and are selected at the scientific organisers' discretion. Abstracts will only be considered if the proposed presenter is registered to attend the meeting (request an invitation).

Attending this event

This is a residential conference, which allows for increased discussion and networking.

  • Free to attend
  • Advanced registration essential (registration information will be available shortly)
  • Catering and accommodation available to purchase during registration

Prior to this meeting, there will be a related discussion meeting 'Frontiers in epigenetic chemical biology' held at the Royal Society London on 22 - 23 May 2017.

Enquiries: Contact the Scientific Programmes team

Event organisers

Select an organiser for more information

Schedule of talks

24 May

09:00-12:30

Session 1

4 talks Show detail Hide detail

Chairs

Professor A. Ganesan, University of East Anglia, UK

09:05-09:30 Catalytic plasticity of DNA methyltransferases: can writers be erasers?

Professor Saulius Klimašauskas, Vilnius University, Lithuania

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09:30-09:45 Discussion

09:45-10:15 Sympathy for the methyl: a 'library-on-library' screening approach to identify small-molecule ligands of methyl-lysine reader proteins

Professor Gianluca Sbardella, University of Salerno, Italy

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10:15-10:30 Discussion

10:30-11:00 Coffee

11:00-11:30 Development of chemical probes targeting JmjC- histone demethylases

Dr Akane Kawamura, University of Oxford, UK

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11:30-11:45 Discussion

11:45-12:15 Chemical epigenetics - inhibitors of methyl lysine readers and sirtuin deacylases

Professor Manfred Jung, University of Freiburg, Germany

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12:15-12:30 Discussion

12:30-13:30

Lunch

13:30-17:15

Session 2

4 talks Show detail Hide detail

Chairs

Dr Akane Kawamura, University of Oxford, UK

13:30-14:00 Targeting the lysine specific demethylase LSD1

Professor A. Ganesan, University of East Anglia, UK

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14:00-14:15 Discussion

14:15-14:45 Targeting lysine acetylation: development of novel epigenetic tools

Professor Panagis Filippakopoulos, University of Oxford, UK

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14:45-15:00 Discussion

15:00-15:30 Tea

15:30-16:00 Transition state mimics as PRMT inhibitors and tools for structural studies

Professor Nathaniel I. Martin, Utrecht University, The Netherlands

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16:00-16:15 Discussion

16:15-17:15 Selected short presentations

17:15-18:15

Poster session

25 May

09:00-12:30

Session 3

4 talks Show detail Hide detail

Chairs

Dr Paola B. Arimondo, CNRS ETaC, France

09:00-09:30 Epigenetic dysfunctions in cancer: a cause or a consequence?

Professor Bozena Kaminska, Nencki Institute of Experimental Biology, Poland

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09:30-09:45 Discussion

09:45-10:15 Epigenetic biomarkers

Professor Carmen Jerónimo, Portuguese Oncology Institute and University of Porto, Portugal

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10:15-10:30 Discussion

10:30-11:00 Coffee

11:00-11:30 Epigenome approaches for identification of treatment resistance in cancer

Professor Lucia Altucci, University of Campania Luigi Vanvitelli, Italy

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11:30-11:45 Discussion

11:45-12:15 Environmental metals, epigenetics and cardiovascular risk: a population-based perspective

Dr Maria Tellez-Plaza, Hospital Clinic of Valencia University, Spain; Johns Hopkins Bloomberg School of Public Health, USA

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12:15-12:30 Discussion

12:30-13:30

Lunch

13:30-17:15

Session 4

4 talks Show detail Hide detail

13:30-14:00 Induction of new fungal natural products by epigenetic modifiers: a systematic approach

Dr Jose-Rubén Tormo, Fundacion MEDINA, Spain

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14:00-14:15 Discussion

14:15-14:45 Dr Clarissa Gerhäuser, German Cancer Center, Germany

14:45-15:00 Discussion

15:00-15:30 Tea

15:30-17:00 Selected short presentations

17:00-17:15 Concluding remarks

Event downloads

Related events

Readers, writers and erasers Kavli Royal Society Centre, Chicheley Hall Newport Pagnell Buckinghamshire MK16 9JJ