Skip to content
What's on

OBSTRACT: interpreting the abstraction of tissue regeneration and re-engineering of female pelvic floor disorders in clinical practice

Discussion meeting


The Royal Society, London, 6-9 Carlton House Terrace, London, SW1Y 5AG


Scientific discussion meeting organised by Dr Sohier Elneil, Professor Sheila MacNeil, Professor Margot Damaser and Dr Gloria Esegbona.

An abstraction of a regenerating pelvic tissue, produced by Dr Gloria Esegbor.

This novel interdisciplinary meeting will bring together scientists and clinicians to review our current understanding of the pathophysiology of female pelvic floor disorders (PFD). Through an analysis of the molecular, cellular, biomechanical and neurological constituents that govern the trauma and subsequent healing process, and correlating this with the ambiguities plaguing the prognosis of surgical repairs. Investigate how our current technologies of regenerative medicine and tissue engineering may offer restorative properties of existing pelvic floor tissue. In addition, explore how these treatment methods can be used in a cost-effective, personalized and scientific approach to care.

The schedule of talks and speaker biographies will be available shortly. Recorded audio of the presentations will be available on this page after the meeting has taken place. 

Poster session

There will be a poster session at 17:00 on Monday 16 October 2017. If you would like to apply to present a poster please submit your proposed title, abstract (no more than 200 word and in third person), author list, name of the proposed presenter and institution to the Scientific Programmes team no later than Friday 1 September 2017. Please note that places are limited and posters are selected at the scientific organiser's discretion. Poster abstracts will only be considered if the presenter is registered to attend the meeting. 

Attending this event

This meeting is intended for researchers in relevant fields: 

  • Free to attend 
  • Limited places, advanced registration is essential
  • An optional lunch can be purchased during registration

Enquiries: Contact the Scientific Programmes team.

Event organisers

Select an organiser for more information

Schedule of talks

16 October


SESSION 1: Regenerating repair

5 talks Show detail Hide detail


Professor Margot Damaser, Cleveland Clinic Foundation

09:40-10:15 Novel approaches for prevention and treatment of pelvic floor disorders

Professor Marianna Alperin, UC San Diego Health

Show speakers

10:15-10:40 Scientific translation discussion

11:00-11:35 The functional anatomy and biomechanics of the female pelvic floor relevant to common disorders

Professor James Ashton-Miller, University of Michigan

Show speakers

11:35-12:10 What are we engineering: How to cause surgical native regeneration of site specific pathoanatomy

Dr Kees Waaldijk, Babbar Ruga National Obstetric Fistula Centre

Show speakers

12:10-12:30 Scientific translation discussion


SESSION 2: Repairing regeneration

5 talks Show detail Hide detail


Dr Sohier Elneil, University College Hospital

13:30-14:05 A regenerative medicine approach to pelvic floor reconstruction: the host response as a primary determinant of success

Professor Stephen F. Badylak, University of Pittsburgh

Show speakers

14:05-14:40 Considerations in designing smarter biomaterials to enhance scarless pelvic regeneration over large distances

Dr Sheila MacNeil, University of Sheffield

Show speakers

14:40-15:10 Clinical translational discussion

15:30-16:05 Regeneration of vaginal support using 3D extracellular matrices: avoiding host inflammatory response to engineered devices

Professor Pamela Moalli

Show speakers

16:40-17:00 Clinical translational discussion

17 October


SESSION 3: Engineering repair

6 talks Show detail Hide detail

09:00-09:35 Potential for biomaterials and bioactive signal expression in engineered materials for pelvic floor disorders

Professor Karl-Dievert Sievert, University Clinic of Rostock

Show speakers

09:35-10:05 Characteristics of vaginal fibroblasts and their attachments to biomaterials using autologous Platelet Rich Plasma

Assistant Professor Oksana Shynlova, University of Toronto

Show speakers

10:05-10:40 Implantation strategy discssion

11:00-11:35 Tissue engineering approaches for treating pelvic organ prolapse using a novel source of mesenchymal stem/stromal cells and new materials

Associate Professor Caroline Gargett, Hudson Institute of Medical Research

Show speakers

11:35-12:10 Modulating the regeneration response: regulation of cellular microenvironments and novel solutions to translational hurdles

Professor Alicia El Haj, Keele University

Show speakers

12:10-12:30 Implantation strategy discussion


SESSION 4: Engineering regeneration

7 talks Show detail Hide detail

13:30-14:00 Non-cellular regenerative medicine techniques for prevention of female pelvic floor disorders

Professor Margot Damaser, Cleveland Clinic Foundation

Show speakers

14:00-14:30 Preclinical animal models to determine mechanisms (paracrine vs MSC incorporation) and clinical assessment of efficacy

Professor Jan Deprest, UZ Leuven

Show speakers

14:30-15:00 Discussion

15:20-15:45 Implantable tribal neuromodulation therapy for over active bladder

Dr Guri Oron, BlueWind Medical

Show speakers

15:45-16:10 Mechanical and etiological aspects of female pelvic floor disorders

Dr Pedro Martins, University of Porto

Show speakers

16:10-16:40 Tissue engineering and regeneration: regulatory routes to the clinic

Ms Alison Wilson, CellData Services

Show speakers

16:40-17:00 Discussion

OBSTRACT: interpreting the abstraction of tissue regeneration and re-engineering of female pelvic floor disorders in clinical practice The Royal Society, London 6-9 Carlton House Terrace London SW1Y 5AG UK