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Mechanics of development

Scientific meeting

Location

Kavli Royal Society Centre, Chicheley Hall, Newport Pagnell, Buckinghamshire, MK16 9JJ

Overview

Theo Murphy international scientific meeting organised by Dr Niamh Nowlan, Professor Celeste Nelson and Professor Philippa Francis-West.

Stain of actin and nuclei in an embryonic lung from a bearded dragon embryo. Image credit: Celeste Nelson, Princeton University

Mechanical forces are critical for embryonic development – yet very little is known about their roles. The meeting will focus on the role of mechanobiology in multiple aspects of embryonic development. The meeting will bring together multidisciplinary research groups in this exciting 'young' area of developmental biology for the first time, enabling formation of a network and sparking new collaborations.

The schedule of talks and speaker biographies can be found below. Recorded audio of the presentations will be available on this page after the meeting has taken place. Meeting papers will be published in a future volume of Philosophical Transactions B.

Poster session

There will be a poster session at 17.00 on Monday 5 February 2018. If you would like to apply to present a poster please submit your proposed title, abstract (not more than 200 words and in third person), author list, name of the proposed presenter and authors' institutions to the Scientific Programmes team no later than Monday 4 December 2017. Please include the text ‘Poster abstract submission’  and the meeting title in the email subject line. Please note that places are limited and are selected at the scientific organisers' discretion. Poster abstracts will only be considered if the presenter is registered to attend the meeting.

Attending this event

This is a residential conference, which allows for increased discussion and networking.

  • Free to attend
  • Advanced registration essential (please request an invitation)
  • Catering and accommodation available to purchase during registration

Enquiries: contact the Scientific Programmes Team

Event organisers

Select an organiser for more information

Schedule of talks

05 February

Session 1 14:00-16:00

Developmental mechanics of branching and folding

2 talks Show detail Hide detail

Chairs

Professor Philippa Francis-West, King's College London, UK

Dr Niamh Nowlan, Imperial College London, UK

14:05-14:45 Active and passive forces in epithelial branching

Professor Celeste Nelson, Princeton University, USA

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14:45-15:30 Models and measurements of cortical folding

Dr Philip Bayly, University of Washington in St. Louis, USA

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15:30-16:00 Coffee

Session 2 16:00-17:00

Keynote 1

1 talk Show detail Hide detail

Chairs

Dr Niamh Nowlan, Imperial College London, UK

16:00-17:00 From mechanical control of organogenesis to human organs-on-chips

Professor Donald Ingber, Wyss Institute at Harvard University, USA

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17:00-18:30

Poster session

06 February

Session 3 08:30-11:00

Biomechanics of skeletal development

4 talks Show detail Hide detail

Chairs

Professor Andrew Pitsillides, The Royal Veterinary College, UK

Dr Chrissy Hammond, University of Bristol, UK

08:30-09:00 Uncovering the mechanistic basis of biomechanical input controlling skeletal development

Professor Paula Murphy, Trinity College Dublin, the University of Dublin, Ireland

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09:00-09:30 New players and concepts in muscoskeletal biomechanics

Professor Elazar Zelzer, Weizmann Institute of Science, Israel

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09:30-10:00 The role of fetal movements in shaping the developing human skeleton

Dr Niamh Nowlan, Imperial College London, UK

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10:00-10:30 Talk title tbc

Professor Catherine K Kuo, University of Rochester, USA

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10:30-11:00 Coffee

Session 4 11:00-12:30

Developmental mechanics of tubes

2 talks Show detail Hide detail

Chairs

Professor Celeste Nelson, Princeton University, USA

Dr Chrissy Hammond, University of Bristol, UK

11:00-11:45 Talk title tbc

Associate Professor Michel Bagnat, Duke University, USA

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11:45-12:30 Talk title tbc

Professor Mark Kahn, University of Pennsylvania, USA

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12:30-13:30

Lunch

Session 5 13:30-15:30

Signalling and mechanotransduction during cardiovascular development

2 talks Show detail Hide detail

Chairs

Professor Philippa Francis-West, King's College London, UK

Professor Andrew Pitsillides, The Royal Veterinary College, UK

13:30-14:15 Talk title tbc

Professor Ellie Tzima, University of Oxford, UK

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14:15-15:00 Tissue mechanics and mechanical forces during cardiovascular development

Dr Julien Vermot, Institut de génétique et de biologie moléculaire et cellulaire, France

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15:00-15:30 Coffee

Session 6 15:30-17:00

Morphodynamics and hemodynamics

2 talks Show detail Hide detail

Chairs

Professor Celeste Nelson, Princeton University, USA

Dr Nic Tapon, The Francis Crick Institute, UK

15:30-16:15 Tissue fluidity promotes epithelial wound healing

Dr Yanlan Mao, University College London, UK

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16:15-17:00 Blood flow and heart formation

Professor Sandra Rugonyi, Oregon Health & Science University, USA

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07 February

Session 7 09:00-11:00

Signalling, self-organisation and pattern formation

2 talks Show detail Hide detail

Chairs

Professor Philippa Francis-West, King's College London, UK

Dr Nic Tapon, The Francis Crick Institute, UK

09:00-09:45 Mechanical control of intestinal organoid formation

Professor Matthias Lutolf, École polytechnique fédérale de Lausanne, Switzerland

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09:45-10:30 Physical organogenesis of the gut

Dr Nicholas R Chevalier, Laboratoire Matière et Systèmes Complexes; CNRS - Université Paris Diderot, France

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10:30-11:00 Coffee

Session 8 11:00-12:30

Keynote 2, summary and close

2 talks Show detail Hide detail

Chairs

Professor Philippa Francis-West, King's College London, UK

11:00-12:00 Mechanbiology of mammalian epidermis

Professor Fiona Watt FMedSci FRS, King's College London, UK

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12:00-12:30 Summary of discussions and closing remarks

12:30-14:00

Lunch

Mechanics of development Kavli Royal Society Centre, Chicheley Hall Newport Pagnell Buckinghamshire MK16 9JJ