Regulation of gene expression from a distance: exploring mechanisms
Image courtesy of Dr Laura Lettice (details discussed in Lettice et al, Hum Mol Genet 17: 978-985, 2008). Expression driven in the developing mouse by the wild-type cat-derived sonic hedgehog ZRS limb enhancer.
Satellite meeting organised by Professor Wendy Bickmore and Professor Veronica van Heyningen FRS
How do distant regulatory elements (enhancers) control spatial and temporal patterns of expression of target genes? This meeting aims to integrate experimental and computational approaches that explore mechanisms of quantitative control of gene expression by enhancers in different model systems. Bringing together researchers from multiple disciplines will provoke new avenues of investigation into long-range gene regulation.
Biographies of the organisers and speakers are available below. Audio recordings are freely available and the programme can be downloaded here.
This meeting was preceded by the related Discussion meeting Regulation from a distance: long-range control of gene expression in development and disease 22 - 23 October 2012.
Enquiries: Contact the events team
Session 1: Enhancer assays – transgenes, genetics, and interactomes
Session 2: Quantitative and dynamic analysis of transcription
Session 3: Quantitative & dynamic analysis of protein binding at regulatory elements
Session 4: Defining enhancers and their mechanisms of action