Research Fellows Directory
Anand Prakash Maurya
Dr Anand Prakash Maurya
University of Birmingham
Plasmid-mediated horizontal gene transfer is one of the prevalent mechanisms for spread and maintenance of multiple antimicrobial resistance determinants among pathogenic bacteria. Occurence of resistance to beta-lactam antibiotics (like penicillins and cephalosporins) in this part of the world is very high which is due to irrational use of antibiotics, lack of proper antibiotic policy (which can lead to suboptimal dosage administration and self medication of antibiotics) and infection control management in hospital settings. This leads persistence, adaptability and survivability of resistance determinants within hospital and community isolates.
Tackling this problem requires multiple approaches one of which is to develop ways to erradicate the genetic elements (plasmids), and the resistance genes they carry, from target bacteria. This project will allow me to work with a world leading plasmid expert who is pioneering such an approach and simultaneously learn more about plasmids.