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Fellows Directory

Andrew Millar

Andrew Millar

Credit: University of Edinburgh

Professor Andrew Millar FRS

Fellow


Elected: 2012

Contact:

Twitter@A_J_Millar

wwwhttp://www.amillar.org

ORCID0000-0003-1756-3654

Biography

Andrew Millar discovered networks of ‘clock genes' that form the 24-hour, biological clock in plants. The clock regulates growth and metabolism through rhythmic, daily activity of the clock genes. He then revealed an evolutionarily older clock in a marine alga, which can operate independently of clock genes. With several collaborators, he showed that this so far unexplained circadian clockwork probably ticks away in other species also, including humans.

Andrew’s team labelled clock genes of the laboratory model plant Arabidopsis thaliana with the bioluminescent protein luciferase, so that the plants glowed in synchrony with the genes’ activity. Conducting similar experiments in the alga Ostreococcus tauri, he found that a clock continued to function even when gene activity was suppressed.

Millar aims to discover the mechanism and function of biological clocks, including the non-genetic rhythm that has caused circadian biologists to rethink their assumptions. Taking a systems approach to his data, he has constructed models of the complex feedback circuits through which living organisms control their activity in night and day, and thus optimise growth.

Professional positions

Professor of Systems Biology, School Of Biological Sciences, University of Edinburgh
Associate Director, SynthSys, University of Edinburgh

Interest and expertise

Subject groups

  • Organismal biology, evolution and ecology
    • Plant sciences / botany
  • Biochemistry and molecular cell biology
    • Biochemistry and molecular biology
  • Other
    • Scientific information provision

Keywords

Arabidopsis thaliana, Ostreococcus tauri, Systems Biology, Mathematical modeling, Phenology, Environmental responses, Marine biology, Plant Signaling Networks, Monetary reform, Multi-scale modeling, Photoperiod responses, Flowering, Seasonal variations, Biological clocks, Circadian rhythms, Circadian oscillators

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