Anthony Epstein was a virologist, noted for discovering a new herpes virus (later named Epstein - Barr virus (EBV) after him) while searching for a causative virus in a lymphoid children's cancer, Burkitt lymphoma (BL). This was the first discovery of a human cancer virus. An essential step in the search involved growing BL cells in the lab and Anthony thus achieved the first culture of any human lymphocytic cell - a technique important for many other investigations.
Silent EBV infection occurs in very young children worldwide, but with cofactors causes BL in African children and cancer of the nose in Southern Chinese adults. It also causes some Hodgkin lymphomas, and cancers in immunosuppressed HIV sufferers and bone marrow recipients. Infection delayed until adolescence may lead to self-limiting glandular fever.
Anthony received many awards, medals, and scientific honours in his life, including four significant international prizes. He served as Royal Society Vice-President and Foreign Secretary for five years, twice on its Council and on many national and international scientific advisory boards. He was knighted in 1991.
Subject groups
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Cell Biology
General microbiology (incl bacteriology and virology)
Awards
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Humphry Davy and Claude Bernard Lecture
On 'The vaccination programme to prevent Epstein-Barr virus-associated cancers in man'.
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Royal Medal
Distinguished for the isolation of the Epstein-Barr virus which is closely associated with Burkitts lymphoma.
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Florey Lecture
On 'Vaccine prevention of virus-induced human cancers'.
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Leeuwenhoek Medal and Lecture
On 'A prototype vaccine to prevent Epstein-Barr (E.B.) virus-associated tumours'.
