Caroline Dean is a biologist who focuses on understanding the molecular controls used by plants to judge when to flower. She is specifically interested in vernalisation — the acceleration of flowering by exposure to periods of prolonged cold. This led to the characterisation of conserved chromatin pathways that converge on the co-transcriptional regulation of an Arabidopsis thaliana floral repressor locus called Flowering Locus C, or FLC. Modulation of these mechanisms has contributed to the adaptation of A. thaliana to its wide geographical range.
For her work addressing fundamental questions in the perception of temperature cues and how modifications in epigenetic mechanisms play an important role in adaptation.
Royal Medals
She has elucidated molecular mechanisms underlying seasonal timing in plants, thus discovering fundamental processes of plant developmental timing and the epigenetic basis of vernalization.