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Research Fellows Directory

Charlotte Stagg

Dr Charlotte Stagg

Research Fellow


University of Oxford

Research summary

Inhibition in the brain decreases the activity of brain cells, providing a necessary brake on their function. However, there is now increasing evidence from animal studies that lowering this inhibition in areas of the brain that control movement is important for learning new skills and for the recovery of function after stroke - processes collectively known as plasticity. It is not yet known how this decrease in inhibition happens in humans, when changes occur over long timescales and in many brain regions. It is important to understand this in order to develop new therapies to improve patients' function after stroke. I will therefore investigate how we can measure such inhibitory changes in humans using new combinations of existing techniques to understand how inhibition changes with plasticity. In addition I propose to study the effects of directly and specifically modulating inhibitory brain activity to promote behavioural improvements using tiny electrical currents applie d via pads placed on the sc

Interests and expertise (Subject groups)

Grants awarded

Exploring the role of inhibition in human motor plasticity.

Scheme: Sir Henry Dale Fellowship

Dates: Apr 2014 - Apr 2019

Value: £838,838

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