Daniel St Johnston is a biologist best known for his key studies on Drosophila fruit flies, which have increased our understanding of how the body axes are correctly established during development. Through his work, Daniel provided the most detailed description ever made of how axis formation arises.
He also pioneered the study of the mechanisms by which messenger RNAs — single strands of nucleic acid used in the construction of proteins — are localised within cells. More recently, his work has focused on cell polarity, evolutionary conserved methods that establish differences between the two ends of a cell. Polarity research is of great importance since cancerous cells often lose their polarity.
Daniel is Professor of Developmental Genetics at the University of Cambridge. He performs his research at the Gurdon Institute, founded to promote research in developmental biology and cancer biology. His laboratory group continues to use Drosophila as a model organism in which to study development.
Wellcome Trust Principal Research Fellow, Gurdon Institute, University of Cambridge
Director of the Gurdon Institute, University of Cambridge
Chair of the Cellular & Developmental Biology, European Research Council
Director, The Company of Biologists
Interest and expertise
- Biochemistry and molecular cell biology
- Biochemistry and molecular biology, Cell biology (incl molecular cell biology)
Cell polarity, Epithelial cells, axis formation, Drosophila, mRNA localisation, polarised secretion, super-resolution microscopy, live imaging, microtubule organisation