Skip to content
Research Fellows Directory

Edward Morrow

Dr Edward Morrow

Research Fellow

Organisation

University of Sussex

Research summary

The genetic code that we all have in common is not identical between all individuals. There are in fact many variations that contribute to variation in a range of traits that we possess and result in differences in things like our appearance and even risk of developing certain diseases. An interesting feature of this variation, when studied in model organisms like the fruit fly, is that some genomes appear to make males perform well and yet the same genome in a female makes a poor performing individual. This pattern suggests that some genetic variation is sexually antagonistic, that is it experiences different and opposing selection pressures depending on the sex of the individual in which it is expressed. While this pattern is clear in datasets from several species of vertebrates and invertebrates we still don't know which parts of the genetic code cause this effect. My research aims to identify precisely those parts of the code and more generally to understand in more detail how the same set of genes can result in a sexually dimorphic phenotype. This could be useful since it may provide valuable information about how diseases may be manifest in the two sexes in different ways, which is a feature of a surprising number of common diseases including several neurological disorders, cardovascular diseases, autoimmune diseases and asthma

Interests and expertise (Subject groups)

Grants awarded

Sexually antagonistic genes: from candidate to cause

Scheme: University Research Fellowship

Dates: Jan 2017 - Dec 2019

Value: £318,135.37

Sexual antagonism and the genetic basis of fitness variation

Scheme: University Research Fellowship

Dates: Jan 2012 - Dec 2016

Value: £512,066.57