Professor Yuk Ming Dennis Lo FRS

Dennis Lo

Director, Li Ka Shing Institute of Health Sciences and  Li Ka Shing Professor of Medicine and Professor of Chemical Pathology, The Chinese University of Hong Kong

Dennis Lo discovered the presence of cell-free fetal DNA, RNA and miRNA in the plasma of pregnant women, creating a paradigm shift in non-invasive prenatal diagnosis. He elucidated the fundamental characteristics of such molecules, developed the technologies for their analysis, conceptualised their use and brought non-invasive prenatal diagnosis to a reality. He achieved the non-invasive prenatal diagnosis of trisomy 21, which has been hailed as the holy grail in prenatal diagnosis. Within a few years, tests, such as sex determination for sex-linked genetic disorders, are clinically used in many centres, replacing the corresponding conventional tests. 

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To recognise, promote, and support excellence in science and to encourage the development and use of science for the benefit of humanity.

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  • Recognising excellence in science
  • Supporting outstanding science
  • Providing scientific advice for policy
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