Dr Jean-Paul Vincent FMedSci FRS
Head, Division of Developmental Biology, MRC National Institute for Medical Research
JP Vincent has used his training in mathematics, physics to devise new techniques to solve important problems in developmental biology. Using novel laser-staining methods he discovered the cortical rotation in frog eggs. He then co-invented caged dye technology, adapted it to lineage tracing and showed that, in living Drosophila embryos, cells acquire identity step by step. Later, he introduced an HRP fusion strategy to study trafficking and epithelial organisation in transgenic animals. This allowed him show that endocytic trafficking of Wnts is spatially and temporally regulated. His work has spurred many others to investigate how trafficking modulate signalling pathways.