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Fellows Directory

Harvey McMahon

Dr Harvey McMahon FRS


Elected: 2008



ORCID 0000-0001-8576-4541


Harvey McMahon conducts a highly creative research programme centred on molecular mechanisms underlying endocytosis. He has discovered different lipid-bending and curvature-sensing mechanisms, and established their generality in facilitating vesicle trafficking between different cellular compartments. The strength of his work is two-fold: first, by undertaking electron microscopic and X-ray diffraction studies, he has been able to formulate novel hypotheses regarding protein function; and second, he has developed imaginative biochemical and cell-free assays to test these structure–function predictions. His research is ground-breaking, having a profound influence on current concepts of molecular processes fundamental to all cells.

Interests and expertise

Subject groups


Endocytosis, Exocytosis, lipid trafficking, Membrane Curvature, Parkinson disease