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Jamel Mankouri

Dr Jamel Mankouri

Dr Jamel Mankouri

Research Fellow

Interests and expertise (Subject groups)

Grants awarded

Why are cellular ion channels required for virus multiplication?

Scheme: University Research Fellowship

Organisation: University of Leeds

Dates: Oct 2016-Sep 2019

Value: £322,395.48

Summary: This project summary is not available for publication.

Host cell ion channel function as a novel target in viral infection

Scheme: University Research Fellowship

Organisation: University of Leeds

Dates: Oct 2011-Sep 2016

Value: £501,086.70

Summary: Newly identified factors shown to be important in leading virus entry, survival and release are cellular ion channels, proteins that act as a pore in the membranes of all cells within the body, permitting the selective passage of ions (such as potassium ions, sodium ions, and calcium ions). Through controlling ion passage, these channels serve many critically important cellular functions including chemical signaling, the regulation of pH, and the regulation of cell volume. Malfunction of ion channels can cause diseases in many tissues. Research in my laboratory focuses on understanding the interaction between clinically important human viruses with cellular ion channels. These studies will allow a better understanding of the host cell processes that viruses require in order to survive.

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