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Research Fellows Directory

Jeffrey Pollard

Professor Jeffrey Pollard

Research Fellow


University of Edinburgh

Research summary

The Royal Society uses case studies of Research Fellows to demonstrate the value of our fellowships to Government and to identify holders who may be suitable for media and other promotion opportunities. Please supply a short lay summary of your research which includes the following: Your research area; a short lay explanation of the science; the potential impact of your work and the possible applications/benefit to society (where applicable). Your summary should be no more than 2000 characters in length.

The Wolfson Research Merit Award is designed to help recruit senior academic back to the UK. In my case this recruitment was from New York to become Director of the MRC Centre for Reproductive Health at the University of Edinburgh in 2013. This transition between countries was made smoother by the award as it helped the University match the differentials between the US and UK salaries to enable my recruitment. My research in Edinburgh studies the role of a type of immune cell, the macrophage, in promoting the spread of cancer a process known as metastasis. We have identified several mechanisms behind these activities and inhibition of these pathways prevents metastatic spread and growth. These studies have led to wide-spread scientific and lay public commentary including in all the major newspapers. Since over 90% of deaths from solid cancers come from metastasis our anticipation is that our research will enhance therapeutic options for this deadly disease and such therapies are being tested now in clinical trials.

Interests and expertise (Subject groups)

Grants awarded

The Metastatic Cascade: Macrophages Lead the Way

Scheme: Wolfson Research Merit Awards

Dates: Mar 2013 - Feb 2018

Value: £150,000