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Research Fellows Directory

Jens Januschke

Dr Jens Januschke

Research Fellow


University of Dundee

Research summary

Cells that divide asymmetrically generate two unequal cells. This is the basis for the specification of different cell types. Cell division further contributes to tissue shape as the orientation of division defines the position where daughter cells are placed. These two features are typical characteristics of stem cells. As malfunction of asymmetric stem cell division and division orientation can lead to pathological situations such as cancer it is important to understand how these processes are controlled normally. Stem cells can divide asymmetrically over many cell cycles. The basis for this is the level of asymmetry within the stem cell. How the cell makes distinctive parts within it different from others is a key problem of cell biology. Moreover, these processes are highly dynamic as these cells divide continuously, raising the question of how stem cells recycle information helping them to remember which way is up. Identifying the molecular components controlling cellula r asymmetry is an important ste

Interests and expertise (Subject groups)

Grants awarded

Recycling polarity mechanisms controlling stem cell polarity in consecutive divisions in the developing Drosophila central nervous system.

Scheme: Sir Henry Dale Fellowship

Dates: Feb 2013 - Feb 2018

Value: £950,354

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