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Research Fellows Directory

Kate Storey

Professor Kate Storey

Research Fellow

Organisation

University of Dundee

Research summary

We are studying how the nervous system develops: in particular, how new nerve cells are born. This involves a cell ceasing division and withdrawing from the proliferative region of the early neural tube. This withdrawal involves the cell detaching from its neighbours in a process known as delamination. This enables the new born nerve cell to migrate to a new position and facilitates its connection with other neurons and so creation of the network that underpins the functional nervous system. Our recent work has uncovered how proteins interact to mediate delamination. In particular, we have discovered a wheel-like microtubule structure and demonstrated how these microtubules interact with other structural proteins (actin and myosin) to release the cell from the ventricular surface of the neural tube.

Interests and expertise (Subject groups)

Grants awarded

Mechanisms regulating neural differentiation

Scheme: Wolfson Research Merit Awards

Dates: May 2015 - Apr 2020

Value: £50,000