Skip to content


Fellows Directory

Kenneth Wolfe

Kenneth Wolfe

Professor Kenneth Wolfe FRS


Elected: 2017




Ken Wolfe studies the evolution of eukaryotic genomes and chromosome organisation. He is best known for his discovery that the genome of the yeast Saccharomyces cerevisiae underwent complete duplication about 100 million years ago, an event we now know to be the result of hybridization between two divergent parental species. This finding reshaped our understanding both of yeast biology, and of mechanisms of genome evolution in eukaryotes. His subsequent discoveries of similar ancient genome duplications in the human lineage, and in almost all families of flowering plants, led to the recognition that whole-genome duplication is a widespread evolutionary mechanism. His group also studies the origin and evolution of mating systems in yeasts, and the process of mating-type switching in which one cell type can change into another by moving or replacing a section of chromosome.

Wolfe is an elected Member of the Royal Irish Academy and of the European Molecular Biology Organization, and a former President of the Society for Molecular Biology and Evolution. He is Professor of Genomic Evolution at University College Dublin.

Professional positions

Professor of Genomic Evolution, Conway Institute of Biomolecular and Biomedical Research

Interest and expertise

Subject groups

  • Microbiology, immunology and developmental biology
    • Genetics (excluding population genetics), General microbiology (incl bacteriology and virology)
  • Organismal biology, evolution and ecology
    • Evolution, Mycology, Plant sciences / botany, Population genetics, Taxonomy and systematics
  • Health and human sciences
    • Medical microbiology


Yeast biology, Yeast genetics, Molecular evolution, Comparative genomics, Evolution of Ascomycetes, Chloroplast DNA, Candida species

Was this page useful?
Thank you for your feedback
Thank you for your feedback. Please help us improve this page by taking our short survey.