Skip to content
Research Fellows Directory

Mark Leake

Professor Mark Leake FInstP, FRMS, FRSB

Research Fellow


University of York

Research summary

I am the Chair of Biological Physics and Director/Founder of the Biological Physical Sciences Institute, University of York, heading an interdisciplinary science team specializing in single-molecule biophysics research. My work on molecular manipulation, ultrasensitive imaging and customized microscope design has led to over 100 articles/books including Nature, Science and PNAS, accruing ca. 3,000 citations. I have presented more than 60 talks worldwide and chaired/organized several international meetings, and I am sole-author of textbooks Single-molecule cellular biophysics Cambridge University Press (2013), Biophysics: Tools & Techniques CRC Press (2016), and Editor of Chromosome Architecture Methods in Molecular Biology (2016), Biophysics of Infection Advances in Experimental Medicine and Biology (2016), and Single molecule cellular biophysics (2013) theme volume in the Royal Society’s flagship biology journal Phil Trans B.

Interests and expertise (Subject groups)

Grants awarded

Inside the black box: probing functional DNA-based nanomachines, one by one

Scheme: University Research Fellowship

Dates: Oct 2012 - Sep 2015

Value: £315,994.57

Bottom-up systems biology using molecular, multidimensional optical proteomics

Scheme: University Research Fellowship

Dates: Oct 2007 - Sep 2012

Value: £525,209.60