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Research Fellows Directory

Matthew Piper

Dr Matthew Piper

Research Fellow


University College London

Research summary

Our research examines the way organisms adjust maximise fitness and health in the face of a varying diet.

In general, organisms must consume diets that do not perfectly match their requirements, meaning some nutrients are under ingested, while others are over ingested. In order to maximize health and minimize the detrimental effects of these mismatches, organisms have evolved a variety of behavioural and physiological adaptations. We use the fruitfly Drosophila melanogaster to uncover these adaptations and understand the mechanisms by which they are effected.

Our research is divided into several areas:

1. What is the definition of a balanced diet for good health?

2. What is the effect of imbalanced diets on gut physiology?

3. What is the effect of imbalanced diets on appetite and feeding behaviour?

4. What is the effect of imbalanced diets on lifespan?

5. how can we use technology to aid in biological discoveries?

Ultimately we seek to discover objective definitions of balanced diets and the mechanisms by which organisms adapt to their diets, in order to enhance health through nutritional manipulations.

Grants awarded

Proteome matching: a novel approach to diet, behaviour and nutrient allocation

Scheme: University Research Fellowship

Dates: Oct 2011 - Apr 2016

Value: £605,138.57