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Research Fellows Directory

Na Wu

Dr Na Wu

Research Fellow

Organisation

University of Oxford

Research summary

My current research is focused on transition metal-catalysed domino reactions of alkenes and alkynes, and related mechanistic studies. These reactions involve the formation of multiple covalent bonds in a single step to construct elaborate polycyclic structures similar to those found in biologically active molecules:

Pd-catalysed enantioselective enyne cyclisations to form quaternary stereocenters via asymmetric counterion directed catalysis;

Mechanistic studies in Pd-catalysed Pauson-Khand reactions initiated by alkynoate chloropalladation;

Enyne cycloisomerisation / Diels-Alder reaction / lactonisation sequences as atom economic routes to fused carbocyclic lactones;

Developing new chiral dienes from extracts of Chinese plants for use in rhodium catalysis.

Interests and expertise (Subject groups)

Grants awarded

Palladium-catalysed cascade cycloisomerisations towards alkaloid-like frameworks

Scheme: Newton International Fellowships

Dates: Jan 2018 - Jan 2020

Value: £99,000

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