Skip to content
Fellows Directory

Nicholas Mitchison

Professor Nicholas Mitchison FRS


Elected: 1967


Nicholas ‘Avrion’ Mitchison discovered the transference of transplantation immunity by sensitised cells, thereby providing the key evidence relating transplantation immunity to hypersensitivity reactions of the ‘delayed’ type. He devised a method for revealing mixtures of cells of different genotypes in vivo and used it to be equal first in demonstrating that the ‘radiation recovery factor’ is a graft of living cells and not a humoral agent. He carried out the most exact quantitative analysis of tolerance hitherto attempted in a cellular system and proved inter alia that persistence of tolerance depends on persistence of antigen. Avrion has thus made notable and distinctive contributions to immunology.