Philip Cohen is a biochemist who has made major contributions to our understanding of protein phosphorylation and its role in cell regulation and human disease. Phosphorylation processes are very important because they control almost all aspects of cellular functions. Abnormal phosphorylation is a factor in many diseases, including cancer, high blood pressure and Parkinson’s.
A major goal of Philip’s research has been to try to understand how cell signalling networks that control inflammation are activated during bacterial and viral infection. He has also identified processes that prevent over-activation of a particular signalling network that causes autoimmune diseases. He has worked on determining which of these signalling targets could potentially be blocked, giving rise to new treatments for many diseases.
For more than ten years, Philip was the Director of the MRC Protein Phosphorylation and Ubiquitylation Unit at the University of Dundee. He has received many national and international awards for his work, including the prestigious Royal Medal of the Royal Society in 2008. Philip was knighted in 1998 for services to biochemistry.
Interest and expertise
Biochemistry and molecular cell biology
Biochemistry and molecular biology
Croonian Medal and Lecture
On 'Discovery of a protein kinase cascade of major importance in insulin signal transduction'.
Louis-Jeantet Prize for Medicine
No citation available for this award.
For his major contribution to our understanding of the role of protein phosphorylation in cell regulation.