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Research Fellows Directory

Stefan Mommer

Dr Stefan Mommer

Research Fellow


University of Cambridge

Research summary

My current research is focused on thiolactone-modified hyaluronic acid polymers. The thiolactones at the hyaluronic acid backbone enable a simple double modification of the polymer. Thiolactones are strained cyclic active esters which allow the selective conversion with amines (e.g. amino acids or peptides). In a second modification step, a guest molecule for host-guest complexation is installed to the polysaccharide. The project aims, to use this final product polysaccharide for tissue engineering applications. Host-guest chemistry allows the cross-linking of these polysaccharides in a non-covalent fashion. The peptides are able to communicate and stimulate with surrounding cells. This hydrogel platform is investigated in relation to cell-hydrogel interactions.

Interests and expertise (Subject groups)

Grants awarded

(Iminium)thiolactone-functional hyaluronic acid for hydrogel-based tissue engineering applications

Scheme: Newton International Fellowships

Dates: Jan 2018 - Jan 2020

Value: £99,000