Professor Stuart Cull-Candy FMedSci FRS

Stuart Cull-Candy is a neuroscientist who is distinguished for his long-standing and innovative work on fast excitatory synaptic signalling in the brain. As one of the pioneers of patch clamp studies of glutamate-activated ion channels, he has made many major contributions to our understanding of how glutamate — the most important transmitter in the brain — mediates signalling between nerve cells.

Stuart was among the first to analyse the biophysical and pharmacological properties of glutamate receptor channels. His studies have revealed many complexities of the different types of glutamate receptor that exist, enabling his lab and others to determine how such receptor channels function in health and disease.

He is noted for being the first to successfully record single-channel currents from AMPA-type glutamate receptors — the major glutamate receptor mediating fast transmission. He also discovered a new form for synaptic plasticity that appears to involve a type of AMPA receptor that underlies several important neurological diseases. Currently, Stuart holds the established Gaddum Chair of Pharmacology and a personal Chair in Neuroscience at University College London.

Subject groups

  • Multicellular Organisms

    Cellular neuroscience, Cellular neuroscience, Pharmacology (non-clinical), Physiology incl biophysics of cells (non-clinical)

Professor Stuart Cull-Candy FMedSci FRS
Elected 2002

Committees

Participated Role
Royal Society Leverhulme Trust Sr. R'search F'ship Panel February 2006 - December 2008 Member
Sectional Committee 8: Multicellular organisms December 2002 - November 2005 Member
Royal Society Leverhulme Trust Sr. R'search F'ship Panel January 2017 - December 2022 Member
Research Grants Committee: Biological Science January 2024 - December 2026 Deputy Chair
Royal Society Wolfson Fellowships Committee January 2024 - December 2026 Member