Research Fellows Directory
Dr Sungho Tak
University College London
Co-Applicant: Prof William Penny.
Functional near-infrared spectroscopy (fNIRS) is an optical technique for measuring brain activity via blood-oxygenation changes. Although there is great interest in using fNIRS to study brain connectivity, current methods are unable to infer the directionality of neuronal connections. Our recent work addressed this shortcoming using dynamic causal modelling (DCM) for fNIRS. Specifically, we proposed a generative model of how observed fNIRS data are caused by interactions among hidden neuronal states. Inversion of this generative model, using an established Bayesian framework, then enabled inference about changes in directed connectivity at the neuronal level. The proposed methods, DCM-fNIRS, have been published in a journal of brain function (NeuroImage 111 (2015) 338-349). We are now proceeding to implement DCM for fNIRS in publicly available software, to disseminate the methods to the fNIRS community. This software will be embodied within the SPM software package.
Interests and expertise (Subject groups)