Yanick Crow is a clinician scientist (MD-PhD), a Clinical Geneticist by training, working at the MRC Human Genetics Unit, Edinburgh, and the Imagine Institute, Paris.
Yanick has an interest in high-penetrance human genetic disorders associated with an up-regulation of type I interferons - a set of inborn errors of immunity resulting from abnormal sensing, inappropriate stimulation, or defective negative regulation of the type I interferon system. The study of these 'type I interferonopathies' provides insights into immunological homeostasis, mechanisms of self/non-self discrimination and viral immunity. Yanick's work has led to the introduction of multiple diagnostic tests used in patient care worldwide. Furthermore, improved understanding of disease pathogenesis has suggested targeted approaches to the treatment of some of these devastating disorders.
Yanick studied medicine at Newcastle University, trained in adult and paediatric medicine in Glasgow and Stirling respectively, and obtained his PhD in molecular genetics from Leeds University. He is a member of the British Society for Genetic Medicine and the British Paediatric Neurology Association, and a Fellow of the Academy of Medical Sciences.
Professional position
- Professor and Programme Leader, MRC Human Genetics Unit, University of Edinburgh
- Team Leader, Institute Imagine, Université Paris
Subject groups
- Biochemistry and molecular cell biology
Molecular immunology
- Microbiology, immunology and developmental biology
Genetics (excluding population genetics)
- Health and human sciences
Medicine, clinical studies, Molecular medicine
