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Regulation of gene expression from a distance: exploring mechanisms

24 - 25 October 2012 09:00 - 16:00

Satellite meeting organised by Professor Wendy Bickmore and Professor Veronica van Heyningen FRS

Event details

How do distant regulatory elements (enhancers) control spatial and temporal patterns of expression of target genes? This meeting aims to integrate experimental and computational approaches that explore mechanisms of quantitative control of gene expression by enhancers in different model systems. Bringing together researchers from multiple disciplines will provoke new avenues of investigation into long-range gene regulation.

Biographies of the organisers and speakers are available below. Audio recordings are freely available and the programme can be downloaded here.

This meeting was preceded by the related Discussion meeting Regulation from a distance: long-range control of gene expression in development and disease 22 - 23 October 2012.

Enquiries: Contact the events team.

Organisers

  • Professor Wendy Bickmore, University of Edinburgh, UK

    Wendy Bickmore is the Head of the Chromosomes and Gene Expression Section at the MRC Human Genetics Unit, MRC IGMM at the University of Edinburgh. Her scientific work is based on the principle being that genes do not function in isolation from their chromosomal and nuclear context. She has pioneered research into the spatial and temporal organisation of the human and mouse genomes, and the implications of this for gene regulation and genome function. Her experimental approaches combine cell biology with genomics, genetics and biochemistry. Wendy is an EMBO member, and a Fellow of both the Royal Society of Edinburgh and the Academy of Medical Sciences.

  • Professor Veronica van Heyningen CBE FRS, University of Edinburgh and UCL, UK

    Veronica van Heyningen took Part II Genetics in Cambridge and gained a doctorate in Oxford exploring somatic cell genetics for early gene mapping. Later in Edinburgh at the MRC Human Genetics Unit she continued with disease gene identification, focussing eventually on developmental eye malformations. From this work evolved her interests in: phenotype variation and modulation; gene regulatory mechanisms and the role of non-coding variation; and gene interactions and networks. She no longer runs a lab but continues to explore these areas as an honorary professor at the Institute of Ophthalmology, University College London and at MRC HGU, University of Edinburgh.