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Investigating the structure of molecules inside cells

Public event

Location

The Royal Society, London, 6-9 Carlton House Terrace, London, SW1Y 5AG

Overview

International Lecture given by Professor Wolfgang Baumeister.

The molecular sociology of the Hela cell nuclear periphery as revealed by cryo-electron tomography. Mahamid J et al. 2016 Visualizing the molecular sociology at the HeLa cell nuclear periphery. Science 351, 969-972

In the past, macromolecular structures have been characterized by methods requiring their isolation and purification. When taken out of their functional context, information about their interactions within the cellular environment is lost. However, it is the interaction between the many molecular species inhabiting cells which underlies cellular functions. Many of them exist only fleetingly or, when integrated in supramolecular complexes, these may be rooted so deeply in cells that they cannot be isolated without affecting their structural integrity. 

Professor Baumeister will discuss a method, cryo-electrontomography, that has the unique potential to study the ‘molecular sociology’ of cells, combining the best structural preservation with 3D high resolution imaging.

The lecture will be webcast live and the video recording will be available shortly after the event.

Attending the event

  • Free to attend
  • No registration required
  • Doors open from 18:00, and seats are allocated on a first-come, first-served basis
  • This event may be popular and entry cannot be guaranteed
  • Live subtitles will be available
  • British Sign Language interpretation will be available on request. Please let the Events team know if you plan to attend at least two weeks before the event.
  • Travel and accessibility information

For all enquiries, please contact the Events team

Investigating the structure of molecules inside cells The Royal Society, London 6-9 Carlton House Terrace London SW1Y 5AG UK