Skip to content
What's on

Synthetic glycobiology

Scientific meeting

Location

Kavli Royal Society Centre, Chicheley Hall, Newport Pagnell, Buckinghamshire, MK16 9JJ

Overview

Theo Murphy international scientific meeting organised by Professor Bruce Turnbull, Dr Anne Imberty and Professor Ola Blixt.

Lectin from Ralstonia solanacearum with carbohydrate ligands. Credit: Serge Pérez and Anne Imberty, graphics by SweetUnityMol (Pérez et al., Glycobiology 2015)

Cell surface carbohydrates mediate diverse biological processes including fertilisation, inflammation and invasion by pathogens. Our understanding of glycobiology has advanced remarkably over recent years, raising the prospect of applying the methods of synthetic biology to reengineer these systems for new and useful purposes. This meeting will bring together chemists, biologists and physicists to define the emerging field of synthetic glycobiology.

The schedule of talks and speaker biographies are available below. Speaker abstracts will be available closer to the meeting. Recorded audio of the presentations will be available on this page after the meeting has taken place. Meeting papers will be published in a future issue of Interface Focus.

Poster session

There will be a poster session on Monday 8 October. If you would like to apply to present a poster please submit your title, proposed abstract (not more than 200 words and in third person), author list, name of the proposed presenter and authors' institutions to the Scientific Programmes team no later than Monday 10 September 2018. Please include the text 'Poster abstract submission' and the meeting title in the subject line. Please note that places are limited and are selected at the scientific organisers' discretion. Poster abstracts will only be considered if the presenter is registered to attend the meeting.

Attending this event

This is a residential conference, which allows for increased discussion and networking.

  • Free to attend
  • Advanced registration essential
  • Catering and accommodation available to purchase during registration

Enquiries: contact the Scientific Programmes team

Event organisers

Select an organiser for more information

Schedule of talks

08 October

Session 1 09:00-12:30

Synthetic glycobiology building blocks from proteins to protocells

4 talks Show detail Hide detail

Chairs

Professor Bruce Turnbull, University of Leeds, UK

09:05-09:30 Lectin engineering: possibilities and perspectives

Professor Jun Hirabayahsi, National Institute of Advanced Industrial Science and Technology, Japan

Show speakers

09:30-09:45 Discussion

09:45-10:15 Computer-aided engineering of reprogrammed carbohydrate-active enzymes for biotechnological applications

Dr Isabelle André, Laboratoire d'Ingénierie des Systèmes Biologiques et des Procédés, France

Show speakers

10:15-10:30 Discussion

10:30-11:00 Coffee

11:00-11:30 Non-canonical amino acids as building blocks for lectins

Dr Birgit Wiltschi, Austrian Centre of Industrial Biotechnology, Austria

Show speakers

11:30-11:45 Discussion

11:45-12:15 Lectin-mediated protocell crosslinking and fusion

Professor Winfried Römer, University of Freiburg, Germany

Show speakers

12:15-12:30 Discussion

12:30-13:30 Lunch

Session 2 13:30-17:00

Engineering novel polysaccharide biomaterials

4 talks Show detail Hide detail

Chairs

Professor Ola Blixt, University of Copenhagen, Denmark

13:30-14:00 Nanoglycobiology based on the S-layer system

Professor Christina Schäffer, Universität für Bodenkultur Wien, Austria

Show speakers

14:00-14:15 Discussion

14:15-14:45 In vitro complex carbohydrate synthesis by membrane-embedded processive glycosyltransferases

Professor Jochen Zimmer, University of Virginia School of Medicine, USA

Show speakers

14:45-15:00 Discussion

15:00-15:30 Tea

15:30-16:00 Getting a grip on glycans in guts and roots with chemical probes

Dr Tom Wennekes, Utrecht University, The Netherlands

Show speakers

16:00-16:15 Discussion

16:15-16:45 Bespoke glycan-presenting surfaces for molecular, supramolecular and cellular interaction studies

Dr Ralph Richter, University of Leeds, UK

Show speakers

16:45-17:00 Discussion

09 October

Session 3 09:00-12:30

Remodelling glycosylation from model systems to living cells

4 talks Show detail Hide detail

Chairs

Dr Anne Imberty, Centre National de la Recherche Scientifique, France

09:00-09:30 Specific lectin-based protein glycoprofiling for cancer diagnostics

Dr Jan Tkac, Slovak Academy of Sciences, Slovakia

Show speakers

09:30-09:45 Discussion

09:45-10:15 A glycosylation programme activated via membrane trafficking controls tissue invasion and remodelling

Dr Frederic Bard, IMCB, A*Star, Singapore

Show speakers

10:15-10:30 Discussion

10:30-11:00 Coffee

11:00-11:30 Chemical tools for engineering glycan interactions at the cell-matrix interface

Professor Kamil Godula, University of California, San Diego, USA

Show speakers

11:30-11:45 Discussion

11:45-12:15 Revealing glycan-mediated interactions through photocrosslinking

Professor Jennifer Kohler, University of Texan Southwestern Medical Center, USA

Show speakers

12:15-12:30 Discussion

12:30-13:30 Lunch

Session 4 13:30-17:00

Synthetic glycobiology towards therapeutic applications

4 talks Show detail Hide detail

Chairs

Professor Bruce Turnbull, University of Leeds, UK

13:30-14:00 Targeting gangliosides using synthetic toxins for pain management

Professor Bazbek Davletov, University of Sheffield, UK

Show speakers

14:00-14:15 Discussion

14:15-14:45 Targeting cancer with modified viruses

Professor Rita Gerardy-Schahn, Hannover Medical School, Germany

Show speakers

14:45-15:00 Discussion

15:00-15:30 Tea

15:30-16:00 Speaker tbc

16:00-16:15 Discussion

16:15-17:00 Panel discussion

Event downloads

Synthetic glycobiology Kavli Royal Society Centre, Chicheley Hall Newport Pagnell Buckinghamshire MK16 9JJ