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Integrated control of cerebral blood flow

Scientific meeting

Location

Kavli Royal Society Centre, Chicheley Hall, Newport Pagnell, Buckinghamshire, MK16 9JJ

Overview

Theo Murphy international scientific meeting organised by Professor Stephen Payne, Dr Clare Howarth, Professor Daniel Bulte and Professor Shieak Tzeng

Credits: Supplied by Rushab Badiani.

The brain regulates cerebral blood flow very tightly to provide a sufficient and continuous supply of oxygen and glucose. It thus has to respond to many different challenges, which have traditionally been considered largely separately. In this meeting we aim to move towards an integrated approach to understanding cerebral blood flow control and to explore its important clinical implications.

The schedule of talks and speaker biographies are below. Speaker abstracts will be available closer to the meeting. Recorded audio of the presentations will be available on this page after the meeting has taken place.

This is a residential conference, which allows for increased discussion and networking.

Attending this event

  • Free to attend
  • Advance registration essential
  • Catering and accommodation available to purchase during registration

Enquiries: contact the Scientific Programmes team

Event organisers

Select an organiser for more information

Schedule of talks

03 December

Session 1 09:00-12:30

Autoregulation

10 talks Show detail Hide detail

Chairs

Professor Daniel Bulte, University of Oxford, UK

09:00-09:05 Welcome session

09:05-09:30 Flow/Pressure Sensing by Ion Channels and the Setting of Cerebral Arterial Tone Development

Professor Donald Welsh, University of Western Ontario, Canada

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09:30-09:45 Discussion

09:45-10:15 Models of cerebral autoregulation

Professor Stephen Payne, University of Oxford, UK

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10:15-10:30 Discussion

10:30-11:00 Coffee

11:00-11:30 Experimental Approaches for Assessment of Cerebral Autoregulation in Humans

Associate Professor, Caroline Rickards, University of North Texas Health Science Center, USA

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11:30-11:45 Discussion

11:45-12:15 Cerebral dysautoregulation in acute stroke – implications for the management of haemodynamic perturbations

Professor Thompson Robinson, University of Leicester, UK

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12:15-12:30 Discussion

12:30-13:30

Lunch

Session 2 13:30-17:00

Reactivity

9 talks Show detail Hide detail

Chairs

Professor Stephen Payne, University of Oxford, UK

13:30-14:00 Effects of Aerobic Exercise on Cerebrovascular Health in Older Adults: Insights from the Brain in Motion Study

Professor Marc Poulin, University of Calgary, Canada

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14:00-14:15 Discussion

14:15-14:45 Cerebrovascular reactivity: biomarker or target?

Professor Daniel Bulte, University of Oxford, UK

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14:45-15:00 Discussion

15:00-15:30 Tea

15:30-16:00 MRI of cerebrovascular reactivity: applications and caveats

Professor Claudine Gauthier, Concordia University/Montreal Heart Institute, Canada

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16:00-16:15 Discussion

16:15-16:45 Mapping Cerebral Blood Flow Regulation in Aging and Dementia

Professor David Mikulis, University of Toronto, Canada

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16:45-17:00 Discussion

04 December

Session 3 09:00-12:30

Neurovascular coupling

9 talks Show detail Hide detail

Chairs

Dr Clare Howarth, University of Sheffield, UK

09:00-09:30 Balancing the brain’s energy supply: Neurovascular coupling in the microvasculature in health and disease

Dr Catherine N. Hall, University of Sussex, UK

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09:30-09:45 Discussion

09:45-10:15 Building a mathematical model of brain energy metabolism

Professor Renaud Jolivet, University of Geneva and CERN, Switzerland

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10:15-10:30 Discussion

10:30-11:00 Coffee

11:00-11:30 Neuronal activity and neuroenergetics with and without CBF

Dr Anna Devor, University of California, San Diego, USA

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11:30-11:45 Discussion

11:45-12:15 The neurovascular unit in health and disease: lessons from animal models

Professor Costantino Iadecola, Weill Cornell Medicine, USA

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12:15-12:30 Discussion

12:30-13:30

Lunch

Session 4 13:30-17:00

Sympathetic control

8 talks Show detail Hide detail

13:30-14:00 Role of cerebral conduit arteries in cerebral blood flow adjustments

Professor Kevin Shoemaker, University of Western Ontario, Canada

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14:00-14:15 Discussion

14:15-14:45 Autonomic interactions with central nervous system blood flow regulation

Dr Aaron Phillips, University of Calgary, Canada

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14:45-15:00 Discussion

15:00-15:30 Tea

15:30-16:00 Integrated Control of Cerebral Blood Flow in Humans

Dr Can Ozan Tan, Harvard Medical School, Spaulding Rehabilitation Hospital, and Massachusetts General Hospital, USA

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16:00-16:15 Discussion

16:15-17:00 Panel discussion/Overview (future directions)

Integrated control of cerebral blood flow

Theo Murphy international scientific meeting organised by Professor Stephen Payne, Dr Clare Howarth, Professor Daniel Bulte and Professor Shieak Tzeng

Kavli Royal Society Centre, Chicheley Hall Newport Pagnell Buckinghamshire MK16 9JJ
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