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Genomic population structures of microbial pathogens

Discussion meeting

Location

The Royal Society, London, 6-9 Carlton House Terrace, London, SW1Y 5AG

Overview

Scientific Discussion meeting organised by Professor Mark Achtman FRS, Professor Kathryn Holt and Professor David Aanensen.

GrapeTree of 1610 Ebola genomes from the West African epidemic of 2013–2016. Credit: from Fig. 3 in Zhou et al., Genome research 28, 1395-1404 (2018)

The comparative genomics of microbial pathogens from all domains of life has become a big data problem. Databases already contain >200,000 assembled genomes from single species but adequate tools to reveal population structures are in their infancy. This meeting will bring together world-class bioinformaticians with experts on bacterial and viral genomes to illustrate multiple approaches to solving this challenge.

Information on the speakers and programme is available below. Speaker abstracts will be available closer to the meeting. Recorded audio of the presentations will be available on this page after the meeting has taken place. Meeting papers will be published in a future issue of Philosophical Transactions of the Royal Society B.

Poster session

There will be a poster session at 17.00 on Monday 23 March. If you would like to apply to present a poster, please submit your title, your abstract (no more than 200 words and in third person), author list, name of the proposed presenter and authors' institutions to the Scientific Programmes team no later than Monday 10 February 2020. Please include the text 'Microbial pathogens: poster abstract' in the subject heading. Please note that places are limited and are selected at the scientific organisers' discretion. Poster abstracts will only be considered if the proposed presenter is registered to attend the meeting.

Attending the event

This meeting is intended for researchers in relevant fields.

  • Free to attend
  • Limited places, advance registration essential
  • An optional lunch can be purchased during registration

Enquiries: contact the Scientific Programmes team

 

Event organisers

Select an organiser for more information

Schedule of talks

23 March

09:00-12:30

Session 1

8 talks Show detail Hide detail

Chairs

Professor Mark Achtman FRS, University of Warwick, UK

09:05-09:30 EnteroBase: core genomes of modern and ancient pathogens

Dr Zhemin Zhou, University of Warwick, UK

Show speakers

09:30-09:45 Discussion

09:45-10:15 Title to be confirmed

10:15-10:30 Discussion

10:30-11:00 Coffee

11:00-11:30 New phylodynamic methods for quantifying pathogen transmission in structured populations - with influenza as a case study

Professor Tanja Stadler, ETH Zurich, Switzerland

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11:30-11:45 Discussion

11:45-12:15 Towards scalable Bayesian genealogical inference with a focus viral outbreak phylodynamics

Professor Philippe Lemey, University of Leuven, Belgium

Show speakers

12:15-12:30 Discussion

12:30-13:30

Lunch

13:30-17:00

Session 2

8 talks Show detail Hide detail

Chairs

Professor Kathryn Holt, Monash University, Australia and London School of Hygiene & Tropical Medicine, UK

13:30-14:00 Title to be confirmed

14:00-14:15 Discussion

14:15-14:45 Population models for multiple disease strains

Professor Julia Gog, University of Cambridge, UK

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14:45-15:00 Discussion

15:00-15:30 Tea

15:30-16:00 Adaptation and diversification within individual human microbiomes

Professor Tami Lieberman, Massachusetts Institute of Technology, USA

Show speakers

16:00-16:15 Discussion

16:15-16:45 Linking pangenomes and metagenomes to investigate fitness determinants among closely related microbes

Professor A Murat Eren (Meren), University of Chicago, USA

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16:45-17:00 Discussion

17:00-18:00

Poster session

24 March

09:00-12:30

Session 3

10 talks Show detail Hide detail

09:00-09:25 Title to be confirmed

09:25-09:35 Discussion

09:35-10:00 Title to be confirmed

10:00-10:10 Discussion

10:10-10:35 New methods with high accuracy and scalability for large-scale phylogenetic estimation

Professor Tandy Warnow, University of Illinois, USA

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10:35-10:45 Discussion

10:45-11:15 Coffee

11:15-11:40 Bacterial population genomics in the era of millions of whole-genome sequences

Professor Jukka Corander, University of Oslo, Norway and Wellcome Sanger Institute, UK

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11:40-11:50 Discussion

11:50-12:15 Title to be confirmed

12:15-12:30 Discussion

12:30-13:30

Lunch

13:30-17:00

Session 4

7 talks Show detail Hide detail

Chairs

Professor Christophe Fraser, University of Oxford, UK

13:30-14:00 The effects on bacterial evolution of the interplay between mobile genetic elements

Dr Eduardo Rocha, Pasteur Institute, France

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14:00-14:15 Discussion

14:15-14:45 Predicting fitness and relative success of bacterial sub-populations using genomic data

Professor Caroline Colijn, Simon Fraser University, Canada

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14:45-15:00 Discussion

15:00-15:30 Tea

15:30-16:00 A scalable analytical pipeline from bacterial genomes to epidemiology

Professor Xavier Didelot, University of Warwick, UK

Show speakers

16:00-16:15 Discussion

16:15-17:00 Panel discussion/overview

Related events

Genomic population structures of microbial pathogens

Scientific Discussion meeting organised by Professor Mark Achtman FRS, Professor Kathryn Holt and Professor David Aanensen.

The Royal Society, London 6-9 Carlton House Terrace London SW1Y 5AG UK
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