Cyborg futures - the challenge of implanting and integrating artificial muscle

Also in “ Scientific meeting”





Discussion meeting organised by Professor Jonathan Rossiter, Dr Nazia Mehrban, Professor Martin Birchall, Dr Majid Taghavi, Professor Dario Farina, Dame Molly Stevens FRS FREng, and Dr Elefteria Iliadou.
This meeting will be the first to address the scientific and social challenges of cyber-physical enhancement, robotic body restoration and implantable artificial muscles. The event brings together world-leading researchers and innovators to explore a cyborg future, with leading presentations and deep discussions in smart materials, implantable artificial muscles, neurointerfacing, soft robots, surgical implantation, bioninterfaces, biomaterials, ethics and more!
Programme
The programme, including speaker biographies and abstracts, will be available soon. Please note the programme may be subject to change.
Poster session
There will be a poster session from 17:00 on Monday 9 June 2025. If you would like to present a poster, please submit your proposed title, abstract (up to 200 words), author list, and the name of the proposed presenter and institution no later than 11 May 2025.
Attending the event
This event is intended for researchers in relevant fields
- Free to attend
- Both virtual and in-person attendance is available. Advance registration is essential. Please follow the link to register.
- Lunch is available on both days of the meeting for an optional £25 per day. There are plenty of places to eat nearby if you would prefer purchase food offsite. Participants are welcome to bring their own lunch to the meeting.
Enquiries: Scientific Programmes team.
Image credit: ©️iStock/ChrisChrisW
Schedule
Chair

Professor Wenhui Song
University College London, UK

Professor Wenhui Song
University College London, UK
Wenhui is a Professor of Biomaterials and Medical Engineering and Head of the UCL Centre for Biomaterials in Surgical Reconstruction and Regeneration at University College London's Division of Surgery and Interventional Science. Her research focuses on multi-responsive functional polymers, nanomaterials, nanocomposites, and biomanufacturing for biomedical applications. She leads a multidisciplinary team developing innovative biomaterials, including functional elastomers and nanocomposites for artificial organs and soft robotics, 3D responsive scaffolds for tissue regeneration and disease modelling, and nanofibre-guided iPSC-derived muscle and neuromuscular junction devices for drug discovery and hybrid biorobotics. Additionally, her work explores piezoelectric nanofibre-based biosensors for artificial muscle applications and AI-assisted artificial hearing systems.
11:45-12:30 |
Panel discussion
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09:00-09:05 |
Welcome by the Royal Society and lead organiser
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09:05-09:15 |
Cyborg futures - engineering implantable artificial muscles
A future where people with disabilities and older people are restored to mobility and health through implantable muscles is very attractive, but faces huge challenges in technology, implantation, control and acceptance. Here we will review the latest progress in fundamental artificial muscle technologies for function restoration developed on the emPOWER project and at the University of Bristol's SoftLab. These include field-driven electrogels, liquid-metal self-oscillating fluid networks and functional hydrogels. ![]() Professor Jonathan RossiterUniversity of Bristol, UK ![]() Professor Jonathan RossiterUniversity of Bristol, UK Jonathan Rossiter is Professor of Robotics at the University of Bristol and Bristol Robotics Laboratory, and Royal Academy of Engineering Chair in Emerging Technologies. He is innovator of smart materials and soft robotics and leads the emPOWER EPSRC Programme Grant on Implantable Artificial Muscles and the VIVO Hub for Enhanced Independent Living. |
09:15-09:45 |
Title to be confirmed
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09:45-10:15 |
From heart pump to face reconstruction: success and challenges in soft actuator implants
Whenever something moves in the human body, our muscles do the work. However, while today it part of everyday clinical practice to replace joints and bones with artificial parts, reconstruction medicine still has great difficulties finding a suitable replacement for damaged or destroyed muscles. There is one muscle in particular whose function is vital and is the subject of several studies, but without convincing results: the heart. Other muscles of the body actually share mechanical similarities with the heart, including the urinal sphincter muscle, which, if damaged, can cause urinary incontinence. Facial muscles also share such similarities and must be replaced after an accident or injury. Although these muscles do not play a vital role in the body, they remain extremely important for patients' quality of life, for example a well-functioning sphincter muscle is critical in order to avoid unpleasant side effects such as needing to wear diapers. The parallels between muscle types could allow the development of universal electroactive multifunctional actuators. Within the Centre for Artificial Muscles (CAM), EPFL, in cooperation with its partners in heart surgery, face reconstruction and urology - University of Bern and Reconstructive Medicine - University of Zürich, aims to become the world's leading reference for the development and clinical transfer of a brand new technological approach for artificial muscles in the human body. The proposed keynote intends to show some examples realised in this new centre. ![]() Dr Yves PerriardÉcole Polytechnique Fédérale de Lausanne, Switzerland ![]() Dr Yves PerriardÉcole Polytechnique Fédérale de Lausanne, Switzerland Yves Perriard obtained his Master in Microengineering from EPFL in 1989 and his PhD from the Electrical Department in 1992. He became cofounder of the company Micro-Beam SA and had the lead of the company until 1998 doing special electrical drives. In 1999 he joined EPFL as Senior Lecturer and in 2003 was appointed Titular Professor and leader of the Integrated Actuators Laboratory. In 2009 he was also appointed Vice-Director of the Microengineering Institute EPFL Neuchâtel. Senior member IEEE and Members EPE, he was also vice-president of the EPE (European Power Electronics) society board in Brussels. Yves Perriard is interested in innovating, analysing and creating new actuators associated with their electronic devices. The multi-disciplinary work of his research makes him strongly in contact with industries in Switzerland and abroad. Yves Perriard has published over 450 papers, 9 patents and is co-author of two books. He is associate editor of several journals. Teacher at the Bachelor and Master level, he has twice received the best teacher award of the Engineering Faculty in 2005 and 2007. More information can be found on the Integrated Actuators Laboratory website (http://lai.epfl.ch). In 2018, he launched a brand new centre at EPFL on artificial muscles thanks to a donation of the Werner Siemens Foundation. |
10:15-10:45 |
Title to be confirmed
![]() Professor Shoji TakeuchiUniversity of Tokyo, Japan ![]() Professor Shoji TakeuchiUniversity of Tokyo, Japan Shoji Takeuchi received BE, ME, and DEng degrees in mechanical engineering from the University of Tokyo, Tokyo, Japan in 1995, 1997, and 2000, respectively. He is currently a Professor in the Department of Mechano-Informatics, Graduate School of Information Science and Technology, University of Tokyo. He has authored more than 250 peer-reviewed publications and filed over 140 patents. He has been recognised with numerous honours, including Young Scientists' Prize, the Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology in 2008, the JSPS prize from Japan Society for the Promotion of Science in 2010, ACS Analytical Chemistry Young Innovator Awards in 2015, and UNESCO Netexplo Award Winner 2019. JSME Micro-Nano Science & Technology Achievement Award in 2022. His current research interests include cultivated meat, 3D tissue fabrication, bioMEMS, implantable devices, artificial lipid bilayer systems, and biohybrid machines. |
10:45-11:15 |
Break
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11:15-11:45 |
Soft microfabricated electrodes: expanding possibilities in neuroprosthetics and neural research (online)
Soft microfabricated electrodes are unlocking new possibilities in neural engineering by providing adaptable, biocompatible interfaces that seamlessly integrate with biological tissues. This talk explores recent advancements in these electrodes, focusing on two key applications: auditory prostheses and brain organoid research. In auditory systems, soft, multichannel implants are especially suited for conforming to the complex, curved surface of the cochlear nucleus, enabling precise simulation for patients who are not candidates for traditional cochlear implants. In brain organoid research, innovative electrode designs such as stretchable MEAs and the self-actuating "e-Flower" electrode provide high-resolution recordings of neural activity, even under mechanical strain. These applications highlight the transformative potential of soft electrodes to bridge the gap between engineered devices and complex neural systems, advancing both clinical therapies and fundamental neuroscience. ![]() Stéphanie LacourÉcole Polytechnique Fédérale de Lausanne ![]() Stéphanie LacourÉcole Polytechnique Fédérale de Lausanne Stéphanie P Lacour is full professor at the School of Engineer at the École Polytechnique Fédérale de Lausanne. She received her PhD in Electrical Engineering from the INSA de Lyon, France, and completed postdoctoral research at Princeton University (USA) and the University of Cambridge (UK). She joined EPFL in 2011. She is founding director of EPFL Neuro X institute - an interschool department focused on interdisciplinary and translational neuro-research located at EPFL-associated campus - Campus Biotech in Geneva. Since January 2025, she is EPFL Vice-President for support for strategic initiatives. |
Chair

Dr Nazia Mehrban
University of Bath, UK

Dr Nazia Mehrban
University of Bath, UK
13:30-13:45 |
Title to be confirmed
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13:45-14:15 |
Title to be confirmed
![]() Dr Ben MetcalfeUniversity of Bath ![]() Dr Ben MetcalfeUniversity of Bath |
14:15-14:45 |
Title to be confirmed
![]() Professor Tamar MakinUniversity of Cambridge, UK ![]() Professor Tamar MakinUniversity of Cambridge, UK Tamar Makin is a Professor of Cognitive Neuroscience at the MRC Cognition and Brain Sciences Unit at Cambridge University and the leader of the Plasticity Lab (www.plasticity-lab.com). Her main interest is understanding how our body representation changes in the brain (brain plasticity). Her primary model for this work is studying hand function and dysfunction, with a focus on how we could use technology to increase hand functionality in able and disabled individuals at all ages. |
14:45-15:15 |
Title to be confirmed
![]() Professor Vivian Mushahwar FAIMBE FCAHSUniversity of Alberta, Canada ![]() Professor Vivian Mushahwar FAIMBE FCAHSUniversity of Alberta, Canada Dr Vivian K Mushahwar is a Professor of Medicine at the University of Alberta and Canada Research Chair (Tier 1) in Functional Restoration. She is also the Director of the Institute for Smart Augmentative and Restorative Technologies and Health Innovations (iSMART) and its business arm, Smart Technology (ST) Innovations. She is a Fellow of the American Institute for Medical and Biological Engineering and a Fellow of the Canadian Academy of Health Sciences. Her work focuses on developing intelligent wearable and implantable neuromodulation devices that restore mobility and prevent secondary complications. She also focuses on developing activity-based therapy rehabilitation interventions that are both efficacious and cost-saving. She initiated the development of micro-implants for stimulating the spinal cord to restore standing and walking after complete spinal cord injury, and demonstrated the benefits of simultaneous arm and leg cycling for improving walking capacity after incomplete spinal cord injury. She and her group invented the wearable garments, Smart-e-Pants and the SOCC, for preventing pressure injuries and deep vein thrombosis, respectively. She holds funding from numerous agencies including the Canadian Institutes of Health Research, New Frontiers in Research Fund, Brain Canada Foundation, and the US Department of Defense. |
15:15-15:45 |
Break
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15:45-16:15 |
Muscles to embody uncertainty, optimally interact with the environment and enhance sensory extraction
In this talk, I will present how humans control their muscles to interact optimally with their environment and how implementing these principles can create versatile artificial muscle systems. Human muscles function as soft actuators with tunable spring-like properties, allowing for adaptive energy exchange, maximal sensory extraction, and compensation for stable, unstable, or uncertain dynamics. By modelling and implementing these adaptive mechanisms, we have developed robotic systems that advance flexible industrial automation, teleoperation, and intuitive, efficient human-robot interaction. ![]() Professor Etienne BurdetUniversity College London, UK ![]() Professor Etienne BurdetUniversity College London, UK Dr Etienne Burdet (https://www.imperial.ac.uk/human-robotics/) is Professor and Chair of Human Robotics at the Imperial College of Science, Technology and Medicine in the UK. He is also a visiting Professor at University College London. He holds an MSc in Mathematics (1990), an MSc in Physics (1991), and PhD in Robotics (1996), all from ETH-Zurich. He was a postdoctoral fellow with TE Milner from McGill University, Canada, JE Colgate from Northwester University, USA and Mitsuo Kawato of ATR in Japan. Professor Burdet's group uses an integrative approach of neuroscience and robotics to: i) investigate human sensorimotor control, and ii) design efficient interfaces for daily living technology and neurorehabilitation, which are tested in human experiments and commercialised. |
16:15-17:00 |
Panel discussion
![]() Dr Martin GarrardUniversity of Bristol, UK ![]() Dr Martin GarrardUniversity of Bristol, UK |
17:00-18:15 |
Poster session
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Chair

Dr Nazia Mehrban
University of Bath, UK

Dr Nazia Mehrban
University of Bath, UK
09:00-09:15 |
Title to be confirmed
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09:15-09:45 |
Biologic interactions of biosynthetic scaffolds composed of poly 4-hydroxy butyrate
The purpose of the talk is to provide an overview on how polymeric biomaterials, and particularly their degradations products, elicit differential responses by the immune cells at the biomaterial-tissue interface. Focusing on the biosynthetic surgical mesh composed of poly (4-hydroxybutyrate) (P4HB), a biomaterial widely used in the biomedical field for hernia repair applications, which has been associated with improved long-term remodelling response and decreased surgical site infection in pre-clinical and clinical studies. In our research, we have identified that 4-hydroxybutyrate (4HB), the main degradation product of P4HB and a short chain fatty acid (SCFA), endogenously secreted in the body, promotes a pro-remodelling, regulatory phenotype of macrophages, which partially contribute to the promotion of site appropriate tissue remodelling. Moreover, through our research it was found that 4HB increased the expression of antimicrobial peptides (AMP) in these macrophages. These studies provided insights on the associated molecular mechanism. It was identified that the mechanisms of AMP secretion are independent of a direct HDAC inhibitory activity, commonly associated with SCFA. Instead, it involves the transcriptional activation of cathelicidin LL-37 through MAP-kinase and NF-KB pathways. Key proteins identified in the transcriptional activation process were GPR109a, JNK, P38, NF-KB, and AP-1. The results of this work expand the understanding of the biologic activity of 4HB in immune system cells and demonstrate its potential to promote a constructive tissue remodelling effect for regenerative medicine applications. ![]() Professor Catalina Pineda MolinaUniversity of Pittsburgh, USA ![]() Professor Catalina Pineda MolinaUniversity of Pittsburgh, USA Dr Catalina Pineda Molina is a Research Assistant Professor at the Department of Surgery, working with Dr Stephen Badylak and Dr George Hussey at the McGowan Institute for Regenerative Medicine a the University of Pittsburgh. Prior to joining the University of Pittsburgh, she was was an Assistant Professor and Head of the Biomedical Engineering Program at Universidad CES, in Medellín, Colombia. In 2014, she received a Fulbright Scholarship to pursue her PhD in Bioengineering. Dr Pineda Molina's research interests are focused on tissue engineering and regenerative medicine applications, particularly developing and evaluating naturally derived biomaterials for the promotion of appropriate constructive tissue remodelling. In particular, she is interested in understanding the molecular mechanisms associated to host-biomaterial interactions and how these can be modulated through molecular bioactive markers, thus advancing in biomaterials science and the immunobiology associated to biomaterials. |
09:45-10:15 |
Title to be confirmed
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10:15-10:45 |
Advancing the biofabrication of tissue building blocks
The seamless integration of biological and engineered components is essential for ensuring the functionality of artificial muscles. Engineered tissues hold great promised in facilitating the integration. Functional tissue building blocks, in particular, will allow the introduction of multiple functionalities into engineered tissues, further enhancing the integration of both biological and engineering components. Our research focuses on developing innovative biofabrication strategies to create functional tissue building blocks and exploring their potential to support the functionality of engineered tissues. In this presentation, I will present our work on microfluidic platforms for generating microvessel templates that guide a vascular integration within engineered tissues both in vitro and in vivo. Additionally, I will discuss how we leverage 3D printing, combined with magnetic control to fabricate thin-layered bioscaffolds and how these bioscaffolds facilitate the creation of 3D vascular networks and 3D biohybrid actuators. Furthermore, I will talk about the generation of magnetically responsive, cell-laden microgels with smart assembly and motion abilities and discuss their potential for dynamic, minimally invasive tissue delivery and interfacing. We believe these biofabricated building blocks provide promising strategies in supporting the implantation, (neuro)vascular integration, and muscular control capabilities of engineered tissues, and will contributed to the development of functional systems for enhanced muscular restoration. ![]() Dr Ruoxiao LieUniversity of Liverpool, UK ![]() Dr Ruoxiao LieUniversity of Liverpool, UK Dr Ruoxiao Xie is a Lecturer in Bioengineering within the School of Engineering at the University of Liverpool. She received her PhD from Tsinghua University in 2020. From 2020 to 2024, she worked as a postdoctoral researcher in Professor Dame Molly Stevens' group in the Department of Materials at Imperial College London. Her research group at the University of Liverpool focuses on developing engineered tissues and organ/organoid-on-a-chip platforms for applications in disease modelling, drug screening, and tissue regeneration. To achieve these goals, her team is also developing innovative biomaterials, biofabrication strategies and bioreactors to enhance tissue patterning and maturation, thus improving the functionality of engineered tissues and organ/organoid-on-a-chip platforms. |
10:45-11:15 |
Break
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11:15-11:45 |
Title to be confirmed
![]() Professor Alicia El Haj FREngUniversity of Birmingham, UK ![]() Professor Alicia El Haj FREngUniversity of Birmingham, UK Professor Alicia El Haj is a leading UK figure in Bioengineering and Regenerative Medicine and has been involved in bringing together interdisciplinary groups within biomedicine, physical sciences and engineering to develop innovative new cell based therapies to the clinic. She has published over a 300 publications in novel enabling technologies such as novel cell and tissue engineering approaches , bioreactors technology, biomaterials and new imaging systems for regenerative medicine with funding from EPSRC, MRC, BBSRC, AR UK Innovate and EU FP in the UK. She is a co-Director of a CDT programme in Regen Med, and a UKRMP Hub in Engineering the Stem cell niche. ISTM has been progressing cell therapies into routine clinical use in orthopaedics for the past 10 years working with consultant orthopaedic surgeons. She is also a Director of a spin out company MICA Biosystems , Ltd involved in translating her patents into clinical use. Professor El Haj was awarded a Royal Society Merit Award in 2014 and in March 2015, was awarded the MRC Suffrage Award for her role in leading women in STEM . |
11:45-12:30 |
Panel discussion
![]() Dr Majid TaghaviImperial College London, UK ![]() Dr Majid TaghaviImperial College London, UK Majid Taghavi is an Associate Professor at Queen Mary University of London and a Research Fellow at Imperial College London, where he leads an interdisciplinary research group focused on Soft Robotics Transducers. He has also worked at SoftLab at the University of Bristol, UK, and the Italian Institute of Technology. Majid's goal is to pioneer the next generation of artificial muscles with enhanced functionalities, ultimately leading to the development of monolithic soft robots for healthcare applications. He has pioneered several artificial muscles, variable stiffness, and self-powered sensing technologies. |
13:30-13:45 |
Title to be confirmed
![]() Professor Martin Birchall FMedSciUniversity College London, UK ![]() Professor Martin Birchall FMedSciUniversity College London, UK |
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13:45-14:15 |
Title to be confirmed
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14:15-14:45 |
Title to be confirmed
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14:45-15:15 |
Title to be confirmed
![]() Dr Avril McCarthySheffield Teaching Hospitals NHS Foundation Trust, UK ![]() Dr Avril McCarthySheffield Teaching Hospitals NHS Foundation Trust, UK |
15:15-15:45 |
Break
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15:45-16:15 |
Title to be confirmed
![]() Dr Dana DamianUniversity of Sheffield, UK ![]() Dr Dana DamianUniversity of Sheffield, UK |
16:15-17:00 |
Panel discussion
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