Jul 19, 2015 - An evolutionary perspective can help unify disparate observations and make testable predictions. We consider an evolutionary model in relation to two mechanistic frameworks of cancer biology: multistage carcinogenesis and the hallmarks of cancer.

L. Nunney, B. Muir

Feb 28, 1901 - The research with which this paper is concerned was undertaken with a view of ascertaining to what extent “connecting threads” are distributed throughout the body of any given plant, and for this purpose the endosperm and the various tissues of

Jul 29, 1994 - The distribution of the immunoreactivity to nitric oxide synthase has been examined from rostral to caudal areas of the rat central nervous system using light microscopy. Endogenous nitric oxide synthase was located using a specific polyclonal

Jan 1, 1808 - My dear sir, In a letter which I had the honour to address to you in the end of the last year, I endeavoured to prove that the matter which composes the bark of trees, previously exists in the cells both of their bark and alburnum, in a fluid state,

May 8, 2001 - Compressed open–cell solid foams frequently exhibit spatially heterogeneous distributions of local stretch. The theoretical aspects of this deformation habit have not been clearly elucidated. Here we propose a simple nonlinear model aimed at

Gustavo Gioia, Yu Wang, Alberto M. Cuitiño

Jan 1, 1872 - My dear Dr. Sharpey,—In my memoir on Calamites, published in the last volume of the ‘Philosophical Transactions,’ I gave two figures of sections of a plant (plate 25. fig. 16 and plate 28. fig. 39) supposed to be a Calamite, but respecting the

Oct 31, 2016 - Bone remodelling is the continuous turnover of bone by resorption and formation. It is controlled by interstitial fluid flow sensed by osteocytes. The refilling of bone resorption sites has been shown to be curvature driven. In vitro, curvature

Jolanda R. Vetsch, Ralph Müller, Sandra Hofmann

Jan 1, 1887 - Several years ago the author discovered the stems and branches of a remarkable plant in the Carboniferous beds at Burntisland, which he described in the volume of the ‘Philosophical Transactions’ for 1873, under the name of Heterangium Grievii.